Interpretation of testing for factor V inhibitors
Only orderable as a reflex. For more information see 5INHE / Factor V Inhibitor Evaluation, Plasma.
Medical Interpretation
Factor V Inhibitor Screen, Plasma
Plasma Na Cit
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Plasma Na Cit | Frozen | 14 days |
Interpretation of testing for factor V inhibitors
Significant bleeding can result from the presence of a coagulation factor inhibitor and could be life threatening. Whether the inhibitor is present due to hemophilia or is of an acquired nature, it greatly complicates the treatment process of a decreased factor level. The titer of the inhibitor may determine the mode of treatment. Bethesda units are a standardization to give a uniform definition of an inhibitor.
Only orderable as a reflex. For more information see 5INHE / Factor V Inhibitor Evaluation, Plasma.
An interpretive report will be provided.
When no significant abnormalities are detected, a simple descriptive interpretation is provided. When abnormal results are detected, a detailed interpretation is given, including an overview of the results and of their significance, a correlation to available clinical information, and elements of differential diagnosis.
No significant cautionary statements
1. Biggs R, Bidwell E. A method for the study of antihemophiliac globulin inhibitors with reference to six cases. Br J Haematol. 1959;5:379-395
2. Hoyer LW: Factor VIII inhibitors. In: Hoyer LW, ed. Progress in Clinical and Biological Research. Vol 150. R Alan Liss Inc; 1984:87-98
3. Kasper CK, Aledort L, Aronson D, et al. Proceedings: A more uniform measurement of factor VIII inhibitors. Thromb Diath Haemorrh. 1975;34(2):612.
4. Kasper C, Ewing N: Acquired inhibitors of plasma coagulation factors. J Med Tech 1986;38:431-439
5. Kottke-Marchant K, ed. Laboratory Hematology Practice. Wiley Blackwell Publishing; 2012
6. Hoffman R, Benz Jr EJ, Silberstein LE, et al, eds: Hematology: Basic Principles and Practice. 7th ed. Elsevier; 2018
A coagulation expert (clinician or hematopathologist) reviews the laboratory data, and an interpretive report is issued.
Not Applicable
85390-26
Test Id | Test Order Name | Order LOINC Value |
---|---|---|
5AINH | FV Inhib Profile Prof Interp | 69049-5 |
Result Id | Test Result Name |
Result LOINC Value
Applies only to results expressed in units of measure originally reported by the performing laboratory. These values do not apply to results that are converted to other units of measure.
|
---|---|---|
607444 | FV Inhib Profile Prof Interp | 69049-5 |
607488 | Reviewed by | 18771-6 |